🔬 Discovery

Antibacterial action of Penicillium (Picado)

Acción antibacteriana de los Penicillium (Picado)

Date
1927 · confidence low
Place
San José, Costa Rica
Credited to
Clodomiro Picado Twight
Field
Life & health

⚠️ Disputed: the sources disagree.

What was discovered

The Costa Rican scientist observed that Penicillium cultures inhibited staphylococcal growth and reported it to the Paris Société de Biologie in 1927. He is cited as a precursor, without isolating the agent, of Fleming's penicillin (1928).

He neither isolated the substance nor tested it clinically; his priority is a historiographical claim and the dates (some sources give 1915-1923) are not well documented.

What it led to

  • Belated recognition of a Latin American precursor of penicillin
  • Studies of fungi and snakes at the Clodomiro Picado Institute

Links

Sources✓ verified 2026-11-04