Autophagy mechanisms
Mecanismo de la autofagia
- Date
- 1992-1993 · confidence high
- Place
- University of Tokyo (Komaba), Tokyo, Japan
- Credited to
- Ōsumi Yoshinori
- People
- 👤 Ōsumi Yoshinori1945–
- Field
- Life & health
What was discovered
Watching yeast cells under the microscope, Ōsumi saw how cells digest their own components in vacuoles, and identified the genes that control the process. He showed the importance of cellular recycling in neurodegenerative disease and cancer.
Nobel Prize in Medicine 2016.
What it led to
- the ATG genes and their human equivalent
- research into neurodegeneration and cancer