Budesonide
Budesonida
- Date
- 1973 · confidence medium
- Place
- Lund, Scania, Sweden
- Credited to
- Arne Thalén and Ralph Brattsand (Draco, a subsidiary later merged into Astra)
- Field
- Life & health
What was discovered
Chemists at Draco in Lund (later part of the Swedish drug company Astra) patented budesonide in 1973, a locally acting corticosteroid with very low systemic absorption, ideal for inhaled treatment of asthma; it went on the market starting in 1981.
The specific credit to Thalén and Brattsand and the location (Astra, in Södertälje) are not confirmed in the Wikipedia article consulted; they are kept as the standard attribution in the pharmacological literature, with medium confidence.
What it led to
- Standard inhaled treatment for asthma and COPD
- Nasal and rectal formulations for allergic rhinitis and inflammatory bowel disease