🔬 Discovery

Cahn-Ingold-Prelog priority rules

Reglas de prioridad Cahn-Ingold-Prelog

Date
1951-1966 · confidence medium
Place
Zurich, Switzerland
Credited to
Robert S. Cahn, Christopher Ingold and Vladimir Prelog (born in Sarajevo)
Field
Matter & energy

What was discovered

A system for naming the three-dimensional configuration of molecules with the R and S descriptors. It is the standard nomenclature of stereochemistry.

Cahn and Ingold proposed the rules in 1951 and 1956; Prelog completed them (1966). Nobel Prize in Chemistry in 1975 for Prelog for the stereochemistry of organic molecules. Prelog was born in Sarajevo and worked in Zurich.

What it led to

  • unambiguous nomenclature of enantiomers
  • description of chiral drugs
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