Cholera bacillus (Vibrio cholerae)
Vibrio cholerae, agente del cólera
- Date
- 1883-1884 · confidence high
- Place
- Calcutta, India (and Alexandria, Egypt)
- Credited to
- Robert Koch; Filippo Pacini (1854)
- People
- 👤 Filippo Pacini1812–1883👤 Robert Koch1843–1910
- Field
- Life & health
⚠️ Disputed: the sources disagree.
What was discovered
Koch isolated the vibrio in Egypt and India and linked it to contaminated water, bacteriologically confirming Snow's epidemiological conclusions.
Filippo Pacini had described it in Florence in 1854, a finding ignored until 1965.
What it led to
- water sanitation and epidemic control
- cholera vaccines (Haffkine, 1892)
- oral rehydration therapy (1968)
Built on
Made possible
- Cholera toxin1959
- Oral rehydration therapy1968-1971
- cholera vaccine