🔬 Discovery

Connectome

Conectoma: mapa completo de las conexiones neuronales

Date
1986-2024 · confidence high
Place
MRC LMB, Cambridge (C. elegans) / Janelia, Virginia and Princeton (Drosophila)
Credited to
Sydney Brenner and John White (C. elegans, 302 neurons, 1986); FlyWire consortium (Drosophila, 140,000 neurons, 2024); Human Connectome Project
People
👤 John White1981–👤 Sydney Brenner1927–2019
Field
Life & health

What was discovered

Complete synaptic reconstruction of a nervous system from serial electron microscopy, first in the worm C. elegans and, in 2024, in the adult fly. It allows the real wiring of the brain to be simulated.

What it led to

  • connectomics and neuroinformatics
  • computational models of whole brains
  • atlases of human brain connectivity by MRI
  • inspiration for AI architectures
🕸️ View in the graph

Built on

Made possible

  • AI-based automatic segmentation of microscopy images

Links