🛠️ Invention or technique

Dark-field ultramicroscope

Ultramicroscopio de campo oscuro

Date
1902-1903 · confidence high
Place
Jena, Thuringia, Germany
Credited to
Henry Siedentopf and Richard Zsigmondy (Zeiss)
Field
Communication

What it is

A microscope that illuminates the sample from the side against a dark background and shows as points of light particles smaller than the resolving power, such as colloidal gold. It was used to study colloids and Brownian motion.

Zsigmondy won the 1925 Nobel Prize in Chemistry for colloid studies with this instrument.

What it led to

  • verification of Brownian motion theory (Perrin, Svedberg)
  • colloid chemistry
  • dark-field microscopy in medicine (spirochaetes)
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Sources✓ verified 2026-11-06