Description of Gilbert's syndrome
Descripción del síndrome de Gilbert
- Date
- 1901 · confidence high
- Place
- Paris, France
- Credited to
- Augustin Nicolas Gilbert
- Field
- Life & health
What was discovered
Gilbert and his colleagues described in Paris, under the name "simple familial cholemia," a benign hereditary disorder of bilirubin metabolism now known as Gilbert's syndrome.
In the German medical literature the same condition is also associated with Jens Einar Meulengracht, who described it later.
What it led to
- Clinical recognition of mild benign jaundice not requiring treatment
- Later study of the UGT1A1 enzyme and its link to certain drug responses