🔬 Discovery

Ephedrine

Efedrina

Date
1885 · confidence high
Place
Imperial University, Tokyo, Japan
Credited to
Nagai Nagayoshi
People
👤 Nagai Nagayoshi1844–1929
Field
Matter & energy

What was discovered

Isolation of the alkaloid from ma huang (Ephedra), used for centuries in Chinese medicine. It became a bronchodilator for asthma and a precursor of amphetamines.

What it led to

  • treatment of asthma
  • synthesis of methamphetamine (Nagai, 1893)
  • decongestants

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