Frank–Starling law of the heart
Ley de Frank-Starling
- Date
- 1895-1915 · confidence medium
- Place
- Munich, Bavaria, Germany
- Credited to
- Ernest Starling y Otto Frank
- Field
- Life & health
What was discovered
German physiologist Otto Frank and British physiologist Ernest Starling formulated the law relating the blood volume reaching the heart to the force of its contraction: greater ventricular filling produces greater stroke volume, a key mechanism for matching cardiac output without nervous regulation.
What it led to
- Foundations of modern cardiovascular physiology
- Clinical management of heart failure
- Models of ventricular function
- Development of experimental hemodynamics