G-quadruplex
- Date
- 1962 · confidence medium
- Place
- Bethesda, Maryland, United States
- Credited to
- David R. Davies
- Field
- Life & health
What was discovered
A secondary nucleic-acid structure formed by stacked guanine tetrads, found in guanine-rich regions such as telomeres; first described by David Davies and colleagues.
What it led to
- Telomere-targeted cancer drugs
- DNA nanotechnology
- Gene regulation research
- DNA-based biosensors