Genetic linkage and chromosome maps (Morgan)
Ligamiento génico, recombinación y mapas cromosómicos
- Date
- 1910-1915 · confidence high
- Place
- The Fly Room, Columbia University, New York, United States
- Credited to
- Thomas Hunt Morgan, Alfred Sturtevant, Calvin Bridges, Hermann Muller
- People
- 👤 Alfred Sturtevant1891–1970👤 Calvin Bridges1889–1938👤 Hermann Müller1876–1931👤 Thomas H. Morgan1866–1945
- Field
- Life & health
What was discovered
Using the fly Drosophila they showed that genes lie on chromosomes in linear order, that the white-eye gene is sex-linked, and that recombination frequency allows them to be mapped (first genetic map, Sturtevant 1913).
Nobel Prize 1933.
What it led to
- classical genetics and gene maps
- population genetics
- human linkage maps and positional cloning
- the Human Genome Project
Built on
Made possible
- Muller's ratchet1932
- Modern evolutionary synthesis1930-1942
- genetic map
- model organisms