🔬 Discovery

Helicobacter pylori and peptic ulcer

Helicobacter pylori como causa de la úlcera gástrica

Date
1982-1984 · confidence high
Place
Royal Perth Hospital, Perth, Australia
Credited to
Barry Marshall and Robin Warren
People
👤 Barry Marshall1951–👤 Robin Warren1937–2024
Field
Life & health

What was discovered

They isolated a spiral bacterium from the stomach and demonstrated, including via Marshall's self-infection, that it causes gastritis and ulcers, until then blamed on stress and acidity.

Nobel Prize 2005.

What it led to

  • curing ulcers with antibiotics
  • reduction in gastric cancer
  • recognition of infections as a cause of chronic diseases

Built on

  • ignored observations of gastric bacteria (19th century)

Made possible

  • urea breath test

📄 Original publication

UNIDENTIFIED CURVED BACILLI IN THE STOMACH OF PATIENTS WITH GASTRITIS AND PEPTIC ULCERATIONBarryJ Marshall, J.Robin Warren · The Lancet · 1984

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