Hershey-Chase experiment
Experimento de Hershey-Chase: los fagos inyectan ADN
- Date
- 1952 · confidence high
- Place
- Cold Spring Harbor Laboratory, New York, United States
- Credited to
- Alfred Hershey and Martha Chase
- People
- 👤 Alfred Day Hershey1908–1997👤 Martha Chase1927–2003
- Field
- Life & health
What was discovered
By labelling phage T2's DNA with 32P and its proteins with 35S they demonstrated that only the DNA enters the bacterium and directs the production of new viruses. It settled the debate over the genetic material.
What it led to
- general acceptance of DNA as the gene
- the race for the structure of DNA
- molecular virology
Built on
Made possible
- DNA double-helix structure1953
- φ29 phage DNA polymerase (strand-displacement amplification)1984-1989
- radioisotopes as biological tracers