🔬 Discovery

Hexamethylenetetramine

Hexametilentetramina

Date
1859 · confidence high
Place
Kazan, Tatarstan, Russia
Credited to
Alexander Butlerov
Field
Matter & energy

What was discovered

Butlerov obtained this cage-shaped heterocyclic compound by reacting formaldehyde (which he himself had synthesized) with ammonia. It became a key building block for phenolic resins, urinary antiseptics and explosive precursors such as RDX.

The exact place where Butlerov carried out the work is not precisely confirmed by the sources consulted; Kazan is assumed, where he was a chemistry professor in 1859.

What it led to

  • Phenolic resins for brake linings and fireproof materials
  • Urinary antiseptic (methenamine)
  • Precursor for explosives such as RDX

Built on

  • Synthesis of formaldehyde

Links

Sources✓ verified 2026-09-28