Iatrochemistry and dose-response principle
Iatroquímica y principio de la dosis
- Date
- c. 1530 · confidence medium
- Place
- Basel, Switzerland
- Credited to
- Paracelsus (Theophrastus von Hohenheim)
- People
- 👤 Theophrastus Bombastus von Hohenheim1493–1541
- Field
- Matter & energy
What was discovered
Paracelsus redirects alchemy towards the preparation of mineral medicines and adds salt as a third principle alongside sulphur and mercury. His maxim 'the dose makes the poison' founds toxicology.
What it led to
- Pharmaceutical chemistry
- Toxicology
- Medical chemistry
Built on
- Sulfur-mercury theory of metals (Jabir)c. 850-950
- Galenic pharmacopoeia
Made possible
- laudanum
- mercurial and antimonial remedies