🛠️ Invention or technique

Infection-and-treatment method against East Coast fever

Método de infección y tratamiento contra la fiebre de la costa oriental

Date
1970s (c. 1975) · confidence medium
Place
Muguga, Kiambu, Kenya
Credited to
Team at the East African Veterinary Research Organization (Radley, Cunningham, Brown and others)
Field
Life & health

⚠️ Disputed: the sources disagree.

What it is

Immunisation of cattle with live Theileria parva sporozoites and a simultaneous dose of long-acting tetracycline, which prevents disease and leaves immunity. It is the most widely used veterinary vaccine against one of the greatest scourges of African cattle.

The method was developed in the 1970s at Muguga; the exact dates of the first trials vary. A parasite with stages in the tick Rhipicephalus appendiculatus that kills over a million cattle a year if uncontrolled.

What it led to

  • vaccination of millions of cattle in East and Central Africa
  • the 'Muguga cocktail' vaccine with three strains
  • a basis for the work of ILRI and GALVmed
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Sources✓ verified 2026-11-04