Jamaican Sickle Cell Cohort Study
Estudio de cohorte de la anemia falciforme de Jamaica
- Date
- 1973 · confidence high
- Place
- Victoria Jubilee Hospital, Kingston, Jamaica
- Credited to
- Graham R. Serjeant and the Sickle Cell Unit (UWI/MRC)
- Field
- Life & health
What was discovered
From 1973 over a hundred thousand newborns in Kingston were screened and those with sickle cell disease followed to describe its complete natural history. It was the first systematic follow-up of children with the disease from birth.
Follow-up continued for decades (over 300 patients with SS genotype since birth). Exact screening figures differ between publications.
What it led to
- penicillin prophylaxis and vaccination in infants with sickle cell disease
- newborn screening for haemoglobinopathies
- definition of the disease's complications (splenic sequestration, pain, stroke)