🔬 Discovery

Knoevenagel condensation

Condensación de Knoevenagel

Date
1894 · confidence medium
Place
Heidelberg, Germany
Credited to
Emil Knoevenagel
Field
Matter & energy

What was discovered

An organic reaction, a variant of the aldol condensation, in which a compound with an active hydrogen adds to a carbonyl group and then dehydrates to give an alpha,beta-unsaturated ketone.

What it led to

  • Hantzsch pyridine synthesis
  • The Gewald reaction and Feist–Bénary furan synthesis

Built on

  • Aldol condensation

Links

Sources✓ verified 2026-09-28