Lisch nodule
Nódulo de Lisch
- Date
- 1937 · confidence high
- Place
- Vienna, Austria
- Credited to
- Karl Lisch
- Field
- Life & health
What was discovered
A pigmented iris hamartoma formed by dendritic melanocytes, a characteristic sign of neurofibromatosis type 1, described by Austrian ophthalmologist Karl Lisch.
What it led to
- became a clinical diagnostic criterion for neurofibromatosis type 1
- enabled non-invasive diagnosis through eye examination
- spurred study of ocular manifestations of systemic genetic diseases