🛠️ Invention or technique

Lobotomy (prefrontal leucotomy)

Lobotomía (leucotomía prefrontal)

Date
1935 · confidence high
Place
Lisbon, Portugal
Credited to
António Egas Moniz (design) and Pedro Almeida Lima (surgeon)
Field
Life & health

⚠️ Disputed: the sources disagree.

What it is

Moniz devised and Almeida Lima performed the first leucotomy, a surgery that severed prefrontal-lobe connections to treat severe psychiatric disorders; it spread to tens of thousands of patients before being abandoned due to its devastating after-effects.

Now considered one of the greatest ethical controversies of 20th-century medicine; the Soviet Union banned it as early as 1950.

What it led to

  • The 1949 Nobel Prize in Medicine, now widely questioned
  • Later replacement by antipsychotic drugs and its ban in several countries

Links

Sources✓ verified 2026-09-25