Mallory body
Cuerpos de Mallory
- Date
- 1911 · confidence high
- Place
- Boston, Massachusetts, United States
- Credited to
- Frank Burr Mallory
- Field
- Life & health
What was discovered
Cytoplasmic inclusions made of damaged intermediate filaments within liver cells, observed by pathologist Frank Burr Mallory and used ever since as a histological marker of liver disease such as alcoholic cirrhosis.
What it led to
- A diagnostic marker in liver histopathology
- Study of alcoholic and non-alcoholic steatohepatitis
- Research on cytoskeletal protein aggregation