🔬 Discovery

Nuclein / nucleic acids (Miescher)

Nucleína (ácidos nucleicos)

Date
1869 · confidence high
Place
University of Tübingen, Germany
Credited to
Friedrich Miescher
People
👤 Joham Friedrich Miescher1844–1895
Field
Life & health

What was discovered

He isolated from leukocyte nuclei (pus from bandages) a phosphorus-rich substance distinct from proteins, which he called nuclein: DNA. Nobody at the time suspected its hereditary role.

What it led to

  • chemistry of nucleic acids (Kossel, Levene)
  • identification of DNA as the genetic material (1944)
  • molecular biology
🕸️ View in the graph

Built on

  • Hoppe-Seyler's physiological chemistry

Made possible

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