🛠️ Invention or technique

Pap test (cervical cytology)

Prueba de Papanicolaou (citología cervical)

Date
1928-1943 · confidence high
Place
Cornell Medical College, New York, United States
Credited to
Georgios Papanikolaou (Georgios Papanicolaou)
Field
Life & health

⚠️ Disputed: the sources disagree.

What it is

A method for detecting cervical cancer from cells in a smear, stained with the Papanicolaou stain. It markedly reduced mortality from cervical cancer.

Papanicolaou presented the finding in 1928 and developed it with Herbert Traut (1943). The Romanian Aurel Babeș published a similar method in 1927-1928, hence priority is disputed. Papanikolaou was born in Kymi (Greece).

What it led to

  • population screening programmes for cervical cancer
  • diagnostic cytology as a specialty

Links

Sources✓ verified 2026-11-04