Polio vaccine (Salk and Sabin)
Vacuna contra la poliomielitis (Salk y Sabin)
- Date
- 1955 · confidence high
- Place
- University of Pittsburgh, Pennsylvania, United States (Salk); Cincinnati (Sabin, oral, 1961)
- Credited to
- Jonas Salk (inactivated, 1955); Albert Sabin (oral attenuated, 1961); cell culture by Enders, Weller and Robbins
- People
- 👤 Jonas Salk1914–1995
- Field
- Life & health
What it is
Vaccines that eliminated the disease that paralysed tens of thousands of children every year, distributed without a patent. Polio is today on the verge of worldwide eradication.
Merged with "Vacuna contra la poliomielitis" (duplicate, 23-09-2026).
What it led to
- Mass vaccination campaigns and the eradication of smallpox (1980)
- The culture of universal childhood vaccination
- Cell culture as the basis of vaccine production
- global eradication campaigns (WHO)
- mass clinical trials
- viral cell culture as a vaccine platform
- public trust in vaccination
Built on
- Poliovirus culture in non-neural tissue (Enders, Weller and Robbins)1949
- HeLa immortal cell line1951
- culturing viruses in cells (1949)
- flu vaccine
- poliovirus culture (Enders, 1949)
- HeLa cells
Made possible
- Synthetic poliovirus (first virus assembled from its sequence)2002
- Rotavac rotavirus vaccine2014
- eradication of smallpox
- cell-culture vaccines
- Expanded Programme on Immunization
- modern inactivated and attenuated virus vaccines