SPf66 synthetic malaria vaccine
SPf66, vacuna sintética contra la malaria
- Date
- 1987 · confidence high
- Place
- Institute of Immunology, Bogotá, Colombia
- Credited to
- Manuel Elkin Patarroyo
- People
- 👤 Manuel Elkin Patarroyo1946–2025
- Field
- Life & health
⚠️ Disputed: the sources disagree.
What it is
The first chemical vaccine made of synthetic peptides against Plasmodium falciparum, tested in humans. Patarroyo donated the patent to the WHO.
Trials in the 1990s in the Gambia and Thailand showed low or no efficacy.
What it led to
- peptide subunit vaccines
- large-scale trials in Africa and Asia