Sulfonamide drugs (Prontosil)
Sulfamidas (Prontosil)
- Date
- 1932–1935 · confidence high
- Place
- Wuppertal (Elberfeld), Germany
- Credited to
- Gerhard Domagk (Bayer/IG Farben); Institut Pasteur (sulfanilamide as the active agent, 1935)
- People
- 👤 Gerhard Domagk1895–1964
- Field
- Life & health
What it is
First widely used synthetic antibacterial, effective against streptococci. It was the first treatment to save lives on a mass scale before penicillin.
What it led to
- Fall in maternal (puerperal) and pneumonia mortality
- Sulfonamide kits in the Second World War
- Derived diuretics and oral antidiabetics
Built on
- Salvarsan (arsphenamine)1909–1910
- Azo dyes
- Dye industry
Made possible
- Oral antidiabetic drugs
- Thiazide diuretics