Synaptic plasticity and long-term potentiation
Plasticidad sináptica y potenciación a largo plazo
- Date
- 1949-1973 · confidence high
- Place
- University of Oslo, Norway
- Credited to
- Donald Hebb (postulate, 1949); Terje Lømo and Timothy Bliss (LTP, 1973); Eric Kandel (Aplysia)
- People
- 👤 Donald Hebb1904–1985👤 Eric Kandel1929–👤 Terje Lømo1935–👤 Timothy Bliss1940–
- Field
- Life & health
What was discovered
Synapses are durably strengthened by repeated activity (LTP in the hippocampus), the cellular basis of learning and memory predicted by Hebb.
Kandel received the Nobel Prize in 2000.
What it led to
- neuroscience of memory
- models of artificial neural networks
- research into Alzheimer's disease and addiction
Built on
Made possible
- Hebbian learning in AI