Tenofovir gel for HIV prevention (CAPRISA 004)
Gel vaginal de tenofovir contra el VIH (CAPRISA 004)
- Date
- 2010 · confidence high
- Place
- Durban, KwaZulu-Natal, South Africa
- Credited to
- Quarraisha and Salim Abdool Karim (CAPRISA)
- People
- 👤 Quarraisha Abdool Karim1960–👤 Salim Abdool Karim1960–
- Field
- Life & health
What was discovered
A trial showing that a tenofovir gel reduced HIV infection in women by 39%. It was the first proof that an antiretroviral drug could prevent sexual transmission.
Published in Science (2010).
What it led to
- oral and injectable pre-exposure prophylaxis (PrEP)
- women-controlled prevention methods
- the dapivirine vaginal ring