Tetanus antitoxin and toxoid
Antitoxina y toxoide tetánico
- Date
- 1890–1924 · confidence medium
- Place
- Paris, France
- Credited to
- Emil von Behring and Shibasaburo Kitasato (antitoxin, Berlin, 1890); Gaston Ramon (toxoid, Institut Pasteur, 1924); P. Descombey (1924)
- People
- 👤 Emil Adolf von Behring1854–1917👤 Gaston Ramon1886–1963👤 Kitasato Shibasaburō1853–1931
- Field
- Life & health
What it is
Serum therapy with antitoxin and then a vaccine with formaldehyde-inactivated toxin (toxoid). It eliminated tetanus from armies and childbirth.
What it led to
- Systematic vaccination of troops in the Second World War
- Combined DTP vaccine and childhood immunisation schedules
- Antibody immunology (first Nobel Prize in Medicine, Behring 1901)
Built on
- Germ theory and pasteurization1857-1865
- Rabies vaccine1885
- Koch's bacterial culture
Made possible
- DTP vaccine
- Diphtheria toxoid