🔬 Discovery

Thiophene

Tiofeno

Date
1882 · confidence high
Place
Zurich, Switzerland
Credited to
Viktor Meyer
Field
Matter & energy

What was discovered

Meyer discovered thiophene while investigating why impure benzene produced a blue stain (the indophenin reaction) with isatin and sulfuric acid, an effect wrongly attributed to benzene itself. He identified a previously unknown sulphur compound, now key to drug chemistry and conducting polymers.

What it led to

  • Sulphur heterocyclic chemistry
  • Thiophene-ring drugs (e.g. clopidogrel)

Built on

  • Kekulé's benzene chemistry

Links

Sources✓ verified 2026-09-28