🔬 Discovery

X-ray induced mutation (Muller)

Mutación inducida por rayos X

Date
1927 · confidence high
Place
University of Texas, Austin, United States
Credited to
Hermann J. Muller; concept of mutation by Hugo de Vries (1901)
People
👤 Hermann Joseph Muller1890–1967
Field
Life & health

What was discovered

He demonstrated that radiation multiplies the mutation rate in Drosophila, proving that genes are physical, alterable entities and that mutation is the source of evolutionary variation.

Nobel Prize 1946.

What it led to

  • radiation genetics and radiological protection
  • mutagenesis in plant breeding
  • understanding of cancer through mutation
  • warnings about nuclear weapons
🕸️ View in the graph

Built on

Made possible

  • targeted mutagenesis
  • genetic screening

📄 Original publication

Artificial Transmutation of the GeneH. J. Muller · Science · 1927

Links