Zanamivir (Relenza)
Zanamivir, antigripal diseñado por estructura
- Date
- 1989 (aprobado en 1999) · confidence high
- Place
- Monash University and CSIRO, Melbourne, Victoria, Australia
- Credited to
- Mark von Itzstein, Peter Colman and team (Biota)
- People
- 👤 Mark von Itzstein1958–👤 Peter Colman1944–
- Field
- Life & health
What it is
An inhibitor of influenza neuraminidase designed from the crystal structure of the enzyme. It was one of the first drugs created by rational design and opened the way to oseltamivir.
What it led to
- oseltamivir (Tamiflu)
- structure-based drug design