🔬 Discovery

Isolation of alcohol (aqua vitae)

Aislamiento del alcohol por destilación del vino (aqua vitae)

Date
c. 1150 · confidence low
Place
School of Salerno, Italy
Credited to
Salerno medical school (Magister Salernus); cryptic recipe in the Mappae clavicula (12th-century addition)
Field
Matter & energy

⚠️ Disputed: the sources disagree.

What was discovered

Distilling wine with cooled alembics made it possible to obtain aqua ardens, concentrated ethanol, one of the first organic substances isolated in Europe.

The refinement of fractional distillation is also attributed to Taddeo Alderotti (13th century).

What it led to

  • Distilling and spirits
  • Pharmaceutical solvents and tinctures
  • Antiseptics
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Built on

Made possible

  • spirit (aguardiente)
  • tinctures
  • spirit lamps

Links

Sources✓ verified 2026-09-23