🔬 Discovery

Transmission of kala-azar by sandflies

Transmisión del kala-azar por flebótomos

Date
1942 · confidence high
Place
Shillong, Meghalaya, India
Credited to
C. S. Swaminath, H. E. Shortt and L. A. P. Anderson
Field
Life & health

What was discovered

They demonstrated for the first time the transmission of Leishmania donovani to human volunteers by the bite of Phlebotomus argentipes, after two decades of failed attempts by the Kala-azar Commission. It closed the disease's cycle and guided its control with insecticides.

The experiment took place at the Pasteur Institute in Shillong with volunteers; it raises ethical questions today.

What it led to

  • DDT spraying campaigns against the sandfly
  • kala-azar elimination programmes in South Asia
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