🔬 Discovery

Central dogma of molecular biology

Dogma central de la biología molecular

Date
1957-1958 · confidence high
Place
Cavendish Laboratory / MRC, Cambridge, United Kingdom
Credited to
Francis Crick
People
👤 Francis Crick1916–2004
Field
Life & health

What was discovered

Information flows from DNA to RNA to protein, and not in reverse from protein. Together with the adaptor hypothesis (tRNA), it fixed the conceptual framework of molecular biology.

What it led to

  • discovery of mRNA and tRNA
  • cracking the genetic code
  • reverse transcriptase as an exception (1970)
  • bioinformatics
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