Hormones and internal secretion (secretin)
Hormonas: secretina y el concepto de secreción interna
- Date
- 1902-1905 · confidence high
- Place
- University College London, England
- Credited to
- William Bayliss and Ernest Starling; Claude Bernard and Brown-Séquard as precursors
- People
- 👤 Charles-Édouard Brown-Séquard1817–1894👤 Claude Bernard1813–1878👤 Ernest Starling1866–1927👤 William Maddock Bayliss1860–1924
- Field
- Life & health
What was discovered
They demonstrated that the intestine releases a substance (secretin) into the blood that stimulates the pancreas without nervous involvement. Starling coined 'hormone' in 1905: chemical messengers that coordinate the body.
What it led to
- endocrinology
- isolation of adrenaline, thyroxine, insulin, steroids
- hormone therapies and contraceptives
- neuroendocrinology
Built on
- Adrenaline (epinephrine) isolated1901
- Claude Bernard's internal milieu (milieu interieur)
- adrenaline (1901)